Having said that, I remember we sometimes had inconclusive data when we
tried to characterize mucosal macrophages isolated from normal human
intestinal tissue. These macrophages are usually CD14 neg, however, in
some instances antibodies showed some binding. We tested 8 different
antibodies, so I dont recall exactly which ones occasionally seemed to
bind and which ones never did. At the time of the experiments we werent
sure whether we just had messed up our experiments or whether that was
evidence for CD14 isoforms.
It would be exciting if there was indeed proof for CD14 isoforms.
Michael