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We have seen a rare example of a T cell malignancy expressing CD20. In
particular, one well documented case of mycosis fungoides demonstrated CD20
expression in addition to the typical CD3+, CD4+, CD7- immunophenotype on a
marrow aspirate. This was confirmed by immunocytochemistry on the biopsy.
Other rare cases have been reported in the literature. As expected, it is
best not to rely on a single immunophenotypic marker to define the lineage of
a neoplastic cell.
Brent Wood MD PhD
Univeristy of Washington
Hematopathology Laboratory
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CD-ROM Vol 3 was produced by Monica M. Shively and other staff at the
Purdue University Cytometry Laboratories and distributed free of charge
as an educational service to the cytometry community.
If you have any comments please direct them to
Dr. J. Paul Robinson, Professor & Director,
PUCL, Purdue University, West Lafayette, IN 47907.
Phone: (765)-494-0757;
FAX(765) 494-0517;
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