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CD8 cells that are CD45RA and CD62L are considered naive. Most (in normal
people) CD8 cells that express CD62L also express CD45RA but some are
CD45RA negative and are considered memory cells. I use the term negative
loosely as the "negative" cells also express some CD45RA. Using CD62L alone
as a naive marker in HIV infected individuals could give grossly inaccurate
results.
Have a nice weekend
Simon Monard
Aaron Diamond Center
NYC
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CD-ROM Vol 3 was produced by Monica M. Shively and other staff at the
Purdue University Cytometry Laboratories and distributed free of charge
as an educational service to the cytometry community.
If you have any comments please direct them to
Dr. J. Paul Robinson, Professor & Director,
PUCL, Purdue University, West Lafayette, IN 47907.
Phone: (765)-494-0757;
FAX(765) 494-0517;
Web